Abstract: Computational fluid dynamics becomes a powerful tool to gain insight into the physical behaviour of the cardiovascular system. An area of cardiovascular disease has received little attention from a computational viewpoint is the analysis of arterial stiffening with age and disease and its relationship with the underlying blood flow behaviour. Due to the complex geometry and material properties of the Aorta, therein, large-scale three dimensional computational models of arterial mechanics can improve our ability to interpret current clinical hemodynamic metrics and to advance our fundamental understanding of the mechanisms of disease progression. In the present research, three dimensional geometry of Aorta is created in CATIA and blood flow behaviour is analysed by Ansys CFX. Mainly, pulsatile flow is investigated for 10 timesteps, Blood is modeled as Newtonian fluid, and the viscous laminar model is employed for the analysis. The CFD simulations successfully produce the effect of blood pressure on the structure of human Aorta; this demonstrated that the methodology can be used to explore blood flow behaviour in Aorta and to relate these to important clinical issues.

Keywords: computational fluid dynamics (CFD), Aorta, Ansys CFX.